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 Hello, My name is Elyse Schechter. I go to Apex High School (roll cougs) where I am a part of the Academy of Information Technology (AOIT) program. In this program, I learned very important soft skills such as interviewing, communicating, and presenting along with hard skills such as computer coding. In this program, I have become a much more confident public speaker and also became Microsoft Word and PowerPoint 2016 certified. I have been exposed to 4 different coding languages (visual basic, C#, SAS, and java) and given the opportunity to participate in an internship at a place of my choice. I interned at the Duke Cancer Institute, which is why this blog was started. Part of my assignments for this internship was to write updates for every 5-10 hours of work and write about what I enjoyed about the workplace. 
Recent posts

My work for the Summer of 2020

 2020 has been a challenging year. The COVID-19 pandemic has made many things unable to happen, or be executed in new and strange ways. Fortunately for me, Dr. Jason Somarelli found a way to provide me and five other students with a way to learn about cancer. We were instructed to choose a web application in order to either learn about cancer vulnerabilities or to answer a biological question. I decided that I wanted to identify compounds to treat Double Hit Lymphoma (DHL) using the DepMap portal.  My grandfather was diagnosed with Double Hit Lymphoma when I was in 7th grade, while he survived, he still suffers from the side effects of experimental treatment plans. DHL is caused by mutations in the MYC and or BCL2/BCL6. It is usually associated with late-stage cancer progression and poor prognosis. But because DHL is a rare subgroup of Lymphoma, there is not yet a standard way for diagnosing and treating it.  In my research, I learned about the MYC gene and how it is indi...

Meeting my expectations

December 2018-February 2019: In the first three months, I have been working I have really enjoyed my experience. I do often feel confused and overwhelmed by certain topics or concepts that need to be discussed, but I am able to do research on them and get caught up to speed. In this first sixth of my internship, I have experienced all three of my learning objectives:  integrating technology into biology and molecular research ,  analyzing molecular biological data and using information technology to communicate complex biological ideas . I feel very confident that this is what I would like to do for a career and I am looking forward to doing more work and learning more about genetics and cancer research. March 2019-May 2019: For the second three months of my internship I have found it slightly hard to concentrate on my assignment. It is very long term and the papers I must read are a little confusing to me. I have worked past this obstacle by finding explanation...

My Workload

My workload has varied throughout my time interning for Dr. Somarelli. During the school year, most of my work will be done over the computer because my schedule will not allow me to drive to Durham every day and do well in my classes. But in the summer I will be going to Durham a lot and experiments in the lab. December 2018-February 2019: The main thing I have done in these months is work on my research, abstract and poster for the Consortium For Canine Comparative Oncology Symposium. This project has been a lot of work and somewhat stressful mostly because it is my first time doing these things and I do not know exactly what I am doing yet. I have also started to help write a review paper on marine-derived anti-cancer compounds. This paper is scheduled to be done in June of 2019. March 2019-May 2019: During these months I have been working on writing a review paper on the anti-cancer properties of marine derived compounds. This has been very interesting bec...

The Experience

As I have started hearing back from colleges and thinking more about where I would like to go for my future, I have thought a lot about my internship. I had an incredible time working with the people I did. They were all smart, passionate, creative, and extremely driven people that I want to be like. Working hands-on in a lab was something I looked forward to doing every single day. I believe that I have found the thing I was meant to do and it is very exciting. I am so thankful for this internship for allowing me to discover that and for AOIT for giving me the opportunity to push myself and to be in this situation.

Hardships Faced

The only hardships I encountered during this internship was that everything I did was very high-level knowledge-based. I did not have the level of knowledge that was required to do the job independently but my superiors were very accommodating and helpful in explaining things to me. As I have taken higher level biology classes, I have begun to learn many things we talked about, but there is still a lot to learn.

Week 8 - 8/19

On Monday, I got to interview Jason. He had a lot of great advice for me for my future. We also discussed how I could continue to work on this throughout the school year. I also used the last and final plate on my LNCAP cells on the Cellvo plates. I will have to do one more split after this to get my final RNA and Protein data and I am super hopeful that I can do it at the end of the week. That way, I can have done a full experiment on my own. On Tuesday, I made my first plasmids. This was really cool. I injected DNA into E. Coli cells so hopefully, they will reproduce it. I also ran RNA extraction on my sample from yesterday and RT. On Wednesday, I looked at the plasmid we set to cure overnight. It was super cool. I also worked on getting organized and preparing to end my time in the lab. I am really hoping that I can get everything done but I don't believe I will have quite enough time. Hopefully, I can come in one Saturday so that I can complete my research project start to ...